Brill-zinsser disease A75.1
Definition
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Late relapse of epidemic spotted fever with a milder and shorter course. In addition to fever and headache, a generalized maculopapular exanthema is usually the only clinical sign.
Etiopathogenesis
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The rickettsiae presumably persist in various organs (e.g. bone marrow) and re-enter the bloodstream about 10-20 years later, triggering typical disease symptoms again (see rickettsioses below).
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Clinic
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- generalized, maculopapular exanthema
- undulating episodes of fever
- neurological symptoms (fasciculations) possible
Diagnostics
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The disease can be diagnosed by PCR or immunofluorescence.
Therapy
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S.u. typhus, epidemic.
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Disclaimer
Please ask your physician for a reliable diagnosis. This website is only meant as a reference.
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Prof. Dr. med. Peter Altmeyer