Synonym(s)
epidemic myalgia; myalgia epidemica; Pleurodynia
HistoryThis section has been translated automatically.
Pickles, 1933
DefinitionThis section has been translated automatically.
Rare complication of a Coxsackievirus infection.
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PathogenThis section has been translated automatically.
Often Coxsackie B viruses (B1, B2, B3, B4, B5); rarely Coxsackie A viruses or echoviruses.
Occurrence/EpidemiologyThis section has been translated automatically.
Most frequently in infants, toddlers or children < 15 LJ. Epidemic in the summer and autumn months.
Clinical featuresThis section has been translated automatically.
- Enanthema, often blisters on the cheek mucosa, palate, uvula and gums.
- General symptoms: fever, headache, vomiting. Myalgia with swelling and pressure sensitivity of the affected muscle groups (especially thorax, back, epigastrium), possibly relieving posture.
LaboratoryThis section has been translated automatically.
Virus cultivation in culture from throat swab or urine, RT-PCR, ELISA.
DiagnosisThis section has been translated automatically.
Lab, histology from muscle biopsy.
Complication(s)This section has been translated automatically.
Pleurodynia, peracute pericarditis, possibly dry pleuritis, myocarditis, encephalitis, rarely paralysis.
TherapyThis section has been translated automatically.
Symptomatically with analgesics like paracetamol (e.g. Ben-u-ron Supp.). Infants/children: 2-3 times/day per 125-500 mg, children/teenagers > 14 years: 2-3 times/day per 1000 mg. In case of complications (e.g. pleurodynia) hospitalization.
Progression/forecastThis section has been translated automatically.
Generally good, duration of the disease 2-3 days. In severe cases with pleuritis or myocarditis in the first months of life, mortality is 5-10%.
LiteratureThis section has been translated automatically.
- Garrison JA et al (2003) Myalgias and arthralgias associated with paclitaxel. Oncology (Huntingt) 17: 271-277
- Gregory PL et al (2002) Musculoskeletal problems of the chest wall in athletes. Sports Med 32: 235-50
- Pichichero M et al (1998) Clinical and economic impact of enterovirus illness in private pediatric practice. Pediatrics 102: 1126-1134
- Pickles W (1933) Bornholm disease. BMJ 2: 1178
- Romero JR (1999) Reverse-transcription polymerase chain reaction detection of the enteroviruses. Arch Pathol Lab Med 123: 1161-1169
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Incoming links (3)
Coxsackie virus infections; Myalgia epidemica; Testicular atrophy, postinfectious;Disclaimer
Please ask your physician for a reliable diagnosis. This website is only meant as a reference.
Prof. Dr. med. Peter Altmeyer