Synonym(s)
Nevus bleu maligner
DefinitionThis section has been translated automatically.
Malignant transformation of a blue nevus, usually starting from the cellular type of the blue nevus, with rapid lymphogenic metastasis.
HistologyThis section has been translated automatically.
In the dermis large globoidal cells in alveolar arrangement, cell and nuclear polymorphism, hyperchromatic giant cells, numerous mitoses, characteristic circumscribed necroses in the tumor parenchyma area. Tumor cells in the marginal sinus of the lymph nodes.
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Differential diagnosisThis section has been translated automatically.
Blue nevus (Naevus bleu); malignant melanoma
TherapyThis section has been translated automatically.
Excision with sufficient safety distance and aftercare. S.u. melanoma, malignant.
Progression/forecastThis section has been translated automatically.
Unfavorable, death mostly within one year due to lymph node, lung, pericardial and brain metastases.
LiteratureThis section has been translated automatically.
- Ariyanayagam-Baksh SM et al (2003) Malignant blue nevus: a case report and molecular analysis. At J Dermatopathol 25: 21-27
- Djawari D et al (1989) Malignant blue nevus. Z Hautkr 64: 51-53
- Mehregan DA et al (1992) Malignant blue nevus: a report of eight cases. J Dermatol Sci 4: 185-192
- Rupec R et al (1993) Malignant blue nevus. dermatologist 44: 164-166
- Shirbacheh MV et al (2003) The use of selective lymphadenectomy in malignant blue naevus of the scalp. Br J Plast Surgery 56: 44-46
- Sonmez Ergun S et al (2001) Guess what! Malignant transformation in a cellular blue nevus of long duration. Eur J Dermatol 11: 265-267
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Disclaimer
Please ask your physician for a reliable diagnosis. This website is only meant as a reference.
Prof. Dr. med. Peter Altmeyer