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Benzyl benzoate

Author:Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Benzyl benzoate; INCI designation: benzyl benzoate

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DefinitionThis section has been translated automatically.

Ester derivative of benzoic acid belonging to the antiparasitosa. Benzyl benzoate is a respiratory poison for parasites and is particularly effective against scabies. It is also effective against lice and can be used as a repellent .

IndicationThis section has been translated automatically.

Skabies, for training in repellents. Also possible with demodex folliculitis. Also used as a fragrance.

Dosage and method of useThis section has been translated automatically.

  • For skabies 10% (children up to 3 years) and 25% (children > 3 years, adults) in emulsions such as benzyl benzoate emulsion 10% or 25% (NRF 11.64.) for external use: On 3 consecutive days in the morning and evening, rub in the whole integument except the head and on the 4th day take a full bath and change bedding and clothing.
  • 5% as a foam for the treatment of mattresses, upholstered furniture and textiles, allow to dry and vacuum after 1 week.
  • 5% as a moist powder for the treatment of carpets, vacuum it off after 1-3 hours.

Undesirable effectsThis section has been translated automatically.

Allergic reactions (component of Peru balsam!), seizures or gasping syndrome (if inadvertently taken or used with infusion systems purified with benzyl alcohol), conjunctivitis

ContraindicationThis section has been translated automatically.

Pregnancy, lactation (application in the breast area), children < 3 years (risk of gasping syndrome: acidosis, CNS damage, respiratory depression, intracranial haemorrhages, hyperbilirubinaemia, leukopenia, thrombopenia, liver damage, purpura, death).

PreparationsThis section has been translated automatically.

Antiscabiosum, Acarosan

Note(s)This section has been translated automatically.

Remember! The use of benzyl benzoate is forbidden for newborns in the USA (deaths due to use of infusion systems purified with benzyl alcohol (so-called gasping syndrome = progressive encephalopathy, metabolic acidosis, bone marrow depression)!

LiteratureThis section has been translated automatically.

  1. Panahi Y et al (2015) The efficacy of topical and oral ivermectin in the treatment of human scabies. Ann Parasitol 61:11-16
  2. Werbrouck J et al (2015) C12-15 alkyl benzoate: a new cosmetic allergen? Contact dermatitis. doi: 10.1111/cod.12419

Authors

Last updated on: 29.10.2020

Author: Prof. Dr. med. Peter Altmeyer

Editor: Dr. med. Stephan Große-Büning