Synonym(s)
ADBAC; Benzalkonium Chlorides; BZK, BKC, BAC, alkyldimethylbenzylammonium Chlorides
DefinitionThis section has been translated automatically.
Substance belonging to the disinfectants(INCI name: benzalkonium chloride). Benzalkonium chloride is a "quaternary ammonium compound" also called quats. Quaternary ammonium compounds have a quaternary nitrogen atom, i.e. a nitrogen atom in which all four hydrogen atoms are replaced by organic radicals.
IndicationThis section has been translated automatically.
Inflammation of the oral mucosa and throat and superficial skin infections.
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Standard concentrationThis section has been translated automatically.
1 mg in lozenges, 0.01-0.02% for mucous membrane rinses, 0.1% for wound rinses, 0.5% in hydrophilic ointments (absorption bases), hydrophilic creams, hydroxyethyl cellulose gel.
Undesirable effectsThis section has been translated automatically.
Allergic reactions are described as type IV contact allergy. The substance is to be assessed as chess sensitizing (Ammann PM et al. 2018). Anaphylactic reactions have also been described after local application.
ContraindicationThis section has been translated automatically.
Children < 4 years.
IncompatibilityThis section has been translated automatically.
Anion-active substances, non-ionic surfactants (e.g. polysorbates), oxidizing agents, bentonite, aerosil, fatty oils, citrates, alginates, iodides, nitrates, heavy metals (silver salts). Adsorption on natural rubber and plastics (polyvinyl chloride)!
PreparationsThis section has been translated automatically.
Dequonal solution/spray, Dorithricin original throat tablets. For skin or instrument disinfection: Lysoform Killavon, Baccalin, Laudamonium, Lysoform, Cutasept, Freka-Derm colourless/coloured.
LiteratureThis section has been translated automatically.
- Ammann PM et al (2018) Disinfectants. Allergo J 27:16-18
- Dao H Jr edt al (2012) Sensitization prevalence for benzalkonium chloride and benzethonium chloride. Dermatitis 23:162-166
- Mezger E et al (2012) Anaphylactic reaction following administration of nose drops containing benzalkonium chloride. Head Face Med 8:29
- Okahara A et al (2013) Local toxicity of benzalkonium chloride in ophthalmic solutions following repeated applications. J Toxicol Sci 38:531-53
Prof. Dr. med. Peter Altmeyer