Base cream dac

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Ambiphilic cream; cremor basalis; DAC Base Cream

Formulation
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The base cream DAC is an ambiphilic cream that can be used universally. In the system of semi-solid and liquid preparations it is positioned between the O/W and W/O systems. There is no inner disperse and no outer homogeneous phase. Hydrophilic and lipophilic phase are bicoherently adjacent to each other.

Water as well as oils can easily be added to this system. 50% water supply turns the ambiphilous cream into a hydrophilic cream or an O/W cream.

If up to 20% oil is added, a lipophilic cream is obtained.

Furthermore the base cream DAC can be mixed with different active agents like glucocorticoids (preferably triamcinolone acetonide, hydrocortisone) and zinc oxide (also in form of Lotio alba).

Rp.

glycerol monostearate 60 4,0
Cetyl alcohol 6,0
Medium chain triglycerides 7,5
Vaselinum album 25,5
Macrogol-20-glycerol monostearate 7,0
Propylene glycol 10,0
Aqua purif. ad 100,0

Active substance-free ambiphilic cream for external use. Apply thinly 1-2 times/day to the affected areas.

Usage period: Tube: 12 months

When zinc is added, a hydrophilic "cream paste" is obtained which is monographed in the DAC and SR. The NRF lists this formulation under NRF 11.109. as "Hydrophilic Zinc Oxide Liniment 25%SR".

Rp.

Zinc Oxide 25,0
glycerol 85% 5,0
Nonionic hydrophilic cream 15,0

Purified water

ad

100,0

Active substance-free hydrophilic cream paste for external application. Apply thinly 1-2 times/day to the affected areas.

Usage period: Tube: 12 months

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Last updated on: 29.10.2020