Bacitracin

Author:Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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DefinitionThis section has been translated automatically.

Topical preparation from the group of polypeptide antibiotics from certain strains of Bacillus subtilis and licheniformis.

Pharmacodynamics (Effect)This section has been translated automatically.

Inhibition of the murein synthesis of the bacterial cell wall.

IndicationThis section has been translated automatically.

Infections with Gram-positive and -negative cocci (spectrum of action similar to that of penicillins).

Dosage and method of useThis section has been translated automatically.

Apply locally 2-3 times/day.

Standard concentrationThis section has been translated automatically.

1%, i.e. 600 IU/g in water absorbing ointments (absorption bases), hydrophilic ointments, ungt. leniens, hydrophilic creams (O/W emulsion ointments), carmellose gel, hydroxyethyl cellulose gel and powders, often combined with neomycin (against gram-negative germs).

Undesirable effectsThis section has been translated automatically.

Danger of sensitization with frequent use. Occasional contact dermatitis. Rarely anaphlactic reactions have been described with local application.

PreparationsThis section has been translated automatically.

Polyspectran (combination with polymyxin-B and neomycin), nebacetin (combination with neomycin), bivacyn (combination with neomycin)

LiteratureThis section has been translated automatically.

  1. Cronin H et al (2009) Anaphylactic reaction to bacitracin ointment. Cutis 83:127-129
  2. Fransway AF et al (2013) North American Contact Dermatitis Group patch test results for 2007-2008 Dermatitis 24:10-21
  3. Spring S et al (2012) Contact dermatitis to topical medicaments: a retrospective chart review from the Ottawa Hospital Patch Test Clinic. Dermatitis 23:210-213
  4. Warshaw EM et al (2012) North American Contact Dermatitis Group, 1994-2008 Positive patch test reactions in older individuals: retrospective analysis from the North American Contact Dermatitis Group, 1994-2008 J Am Acad Dermato l66:229-240

Authors

Last updated on: 29.10.2020

Author: Prof. Dr. med. Peter Altmeyer