Medicinal products which have either a fungistatic or fungicidal action. See Table 1 for the classification.
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Antimycotics
DefinitionThis section has been translated automatically.
ClassificationThis section has been translated automatically.
Polyenes (polyene macrolides)
Imidazoles (systemic and local; local in concentrations of 1-2%)
- Bifonazole
- Clotrimazole
- Croconazole
- Econazole
- Fenticonazole
- Isoconazole
- Ketoconazole
- Miconazole
- Oxiconazole
- Sertaconazole
- Tioconazole
Triazoles (used systemically)
Allylamine
- Naftifine
- Terbinafine
- Hydroxypiridone
- Ciclopirox
Echinocandins (lipopeptides; inhibitors of glycan synthase)
Morpholine
Various
- Dequalinium chloride
- Pyrithione Zinc
- Griseofulvin (in D out of trade)
- Fenticlor
- Flucytosine
- Tolciclate
- Tolnaftate
- Undecylenic acid
IndicationThis section has been translated automatically.
see below Mycoses; see below Dermatomycoses
LiteratureThis section has been translated automatically.
- Geier J et al (2016) News on the epicutaneous test series of the German Contact Allergy Group. Dermatology at work and in the environment 64: 70-75
TablesThis section has been translated automatically.
Overview of antimycotic drugs and their activity spectra
Group/Substance |
Forms of application |
Spectrum of action |
||
Dermatophytes |
yeasts |
Moulds |
||
Polyenes | ||||
amphotericin B |
top., p.o., i.v. |
+ |
||
Natamycin |
top., p.o. |
|
+ |
|
Nystatin |
top., p.o. |
|
+ |
|
Imidazole | ||||
Bifonazole |
top. |
+ |
+ |
+ |
Clotrimazole |
top. |
+ |
+ |
+ |
Croconazole |
top. |
+ |
+ |
+ |
Econazole |
top. |
+ |
+ |
+ |
Fenticonazole |
top. |
+ |
+ |
+ |
Isoconazole |
top. |
+ |
+ |
+ |
Ketoconazole |
top., p.o. |
+ |
+ |
+ |
Miconazole |
top., p.o., i.v. |
+ |
+ |
+ |
Oxiconazole |
top. |
+ |
+ |
+ |
Sertaconazole |
top. |
+ |
+ |
+ |
Tioconazole |
top. |
+ |
+ |
+ |
Triazoles | ||||
Fluconazole |
p.o., i.v. |
+ |
+ |
(+) |
Itraconazole |
p.o., i.v. |
+ |
+ |
+ |
Voriconazole |
p.o., i.v. |
|
+ |
+ |
Allylamine | ||||
Naftifine |
top. |
+ |
||
Terbinafine |
top., p.o. |
+ |
||
Hydroxypiridone | ||||
Ciclopirox |
top. |
+ |
+ |
+ |
Echinocandine | ||||
Caspofungin |
i.v. |
|
+ |
+ |
Morpholine | ||||
Amorolfine |
top. |
+ |
+ |
+ |
Various | ||||
Dequalinium chloride |
top. |
(+) |
+ |
(+) |
Pyrithione Zinc |
top. |
(+) |
+ |
(+) |
Griseofulvin (in D out of trade) |
top., p.o. |
+ |
|
|
Fenticlor |
top. |
+ |
+ |
|
Flucytosine |
i.v. |
(+) |
(+) |
|
Tolciclate |
top. |
+ |
|
|
Tolnaftat |
top. |
+ |
|
|
Undecylenic acid |
top. |
|
+ |
|