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Anosacral cutaneous amyloidosisL99.0; E85.4

Last updated on: 14.08.2023

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DefinitionThis section has been translated automatically.

Rare primary cutaneous amyloidosis in the anosacral region that has been described only in Asian patients .

ManifestationThis section has been translated automatically.

Mostly advanced age; > 60 years.

Clinical featuresThis section has been translated automatically.

The lesions appear as moderately sharply demarcated brown-colored patches or plaques that spread in lines from the anus to the sacral region. Itching does not appear to be a leading symptom.

HistologyThis section has been translated automatically.

Detection of papillary amyloid depots.

Differential diagnosisThis section has been translated automatically.

The disease can easily be misdiagnosed as lichen simplex chronicus, or as postinflammatory hyperpigmentation or a tinea

LiteratureThis section has been translated automatically.

  1. Gerhardt CA et al (2022) Anosacral amyloidosis in a Chinese-Caribbean male. JAAD Case Rep 21:46-48
  2. Wang WJ et al (2000) Anosacral cutaneous amyloidosis: a study of 10 Chinese cases. Br J Dermatol 143:1266-1269.
  3. Niiyama S et al (2006) Hyperkeratotic lichenified skin lesion of gluteal region. J Dermatol 33:779-782.

Last updated on: 14.08.2023