Anosacral cutaneous amyloidosis L99.0; E85.4

Last updated on: 14.08.2023

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Definition
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Rare primary cutaneous amyloidosis in the anosacral region that has been described only in Asian patients .

Manifestation
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Mostly advanced age; > 60 years.

Clinical features
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The lesions appear as moderately sharply demarcated brown-colored patches or plaques that spread in lines from the anus to the sacral region. Itching does not appear to be a leading symptom.

Histology
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Detection of papillary amyloid depots.

Differential diagnosis
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The disease can easily be misdiagnosed as lichen simplex chronicus, or as postinflammatory hyperpigmentation or a tinea

Literature
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  1. Gerhardt CA et al (2022) Anosacral amyloidosis in a Chinese-Caribbean male. JAAD Case Rep 21:46-48
  2. Wang WJ et al (2000) Anosacral cutaneous amyloidosis: a study of 10 Chinese cases. Br J Dermatol 143:1266-1269.
  3. Niiyama S et al (2006) Hyperkeratotic lichenified skin lesion of gluteal region. J Dermatol 33:779-782.

Outgoing links (1)

Lichen simplex chronicus;

Disclaimer

Please ask your physician for a reliable diagnosis. This website is only meant as a reference.

Last updated on: 14.08.2023