Synonym(s)
HistoryThis section has been translated automatically.
Annessi 2003
DefinitionThis section has been translated automatically.
Etiologically unexplained, chronic, lichenoid dermatitis with truncated, large, reddish or brownish, asymptomatic or slightly itchy patches or tender, barely palpable, scale-free plaques, which are homogeneously or annularly configured and may have central hypopigmentation.
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Occurrence/EpidemiologyThis section has been translated automatically.
EtiopathogenesisThis section has been translated automatically.
The aetiopathogenesis of ALDY is currently unknown (Annessi G et al. 2022), although immunohistochemical findings suggest that the disease could be caused by a cytotoxic T-cell-mediated immune response, as is the case with other lichenoid skin reactions. A Borrelia infection has been discussed.
ManifestationThis section has been translated automatically.
LocalizationThis section has been translated automatically.
Clinical featuresThis section has been translated automatically.
HistologyThis section has been translated automatically.
Mild or severe (psoriasiform) acanthosis. Orthokeratosis. Prominent, lichenoid interface dermatitis, which is mainly detectable at the tips of the retele ridges, but also in bands. Immunohistologically, CD8/TIA-1- and CD4-positive T-lymphocytes are particularly impressive. CD8/TIA-1-positive cells are mainly found intraepithelially. The analysis of the TCR-γ chain gene rearrangement showed polyclonality in all cases examined.
DiagnosisThis section has been translated automatically.
Differential diagnosisThis section has been translated automatically.
Mycosis fungoides: Rarely found at the preferred age of childhood anular lichenoid dermatosis. Histologically, MF shows an inverse pattern of CD4-positive T-lymphocytes intraepithelially to the lichenoid dermatosis.
Erythema anulare centrifugum: Dynamic course, clearly palpable anular plaques (consistency of a wet wool thread). Histologically a lichenoid pattern is missing.
Tinea corporis: Dynamic course, always epidermal component with scaling, blister or pustular formation. Fungal detection is successful in non-pretreated flocks.
Erythema chronicum migrans: Dynamic course, detection of Borrelia bacteria! Histology: No interface dermatitis.
Erythema anulare rheumaticum: Volatile skin component in rheumatic fever (general symptoms are always present). Clinically there are borderline, polycyclic, reddish-brownish, non-pruritic erythema.
TherapyThis section has been translated automatically.
Local therapy with glucocorticoids. The disease proves to be very steroid-sensitive. Recurrence after discontinuation of steroidal therapy is probable.
Progression/forecastThis section has been translated automatically.
LiteratureThis section has been translated automatically.
- Annessi G et al. (2022) Annular Lichenoid Dermatitis (of Youth). Dermatopathology (Basel) 9:23-31.
- Annessi G et al. (2003) Annular lichenoid dermatitis of youth. J Am Acad Dermatol 49: 1029-1036
- Cesinaro AM et al. (2009) Annular lichenoid dermatitis of youth... and beyond: A series of 6 cases. Am. J. Dermatopathol 31: 263-267.
- Fabroni C et al (2010) Annular lichenoid dermatitis. Clin Exp Dermatol 35: 921-923.
- Huh W et al. (2010) Annular lichenoid dermatitis of youth: Report of the first Japanese case and published work review. J Dermatol 37: 531-533.
- Kleikamp S et al. (2010) Annular lichenoid dermatosis of childhood - another case in a 12-year-old girl. JDDG 6: 653-656
- Tsoitis G et al (2009) Annular lichenoid dermatitis of youth. J Eur Acad Dermatol Venereol 23, 1339-1340.
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Outgoing links (5)
Erythema anulare centrifugum; Erythema anulare rheumaticum; Erythema migrans; Mycosis fungoides; Tinea corporis;Disclaimer
Please ask your physician for a reliable diagnosis. This website is only meant as a reference.
Prof. Dr. med. Peter Altmeyer
