DefinitionThis section has been translated automatically.
Benign fibroblastic soft tissue tumor, rarely recurring postoperatively, which occurs preferably in the genital area.
ManifestationThis section has been translated automatically.
Women are more frequently affected than men.
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LocalizationThis section has been translated automatically.
Genital area, also extremities.
Clinical featuresThis section has been translated automatically.
Symptomless, firm, reddish or slightly bluish shimmering lumps. The tumours do not grow larger than 3.0 cm in women, but up to 25 cm in men.
HistologyThis section has been translated automatically.
Sharply defined tumour with numerous thick-walled hyalinised vessels, abundant spindle cells and interspersed adipocytes. Mitoses can be numerous. Lipogenic differentiation is not uncommon. The tumor parenchyma often expresses CD34, alpha-smooth muscle actin and desmin, but not S-100 protein and pancytokeratin.
LiteratureThis section has been translated automatically.
- Ahmadnia HJ et al (2014) Angiofibroma of the vulva. Cutan Med Surg 18:203-205
- Mentzel T (2016) Mesenchymal tumors of the skin. In: Cerroni L et al. histopathology of the skin. Springer-Verlag Berlin Heidelberg New-York S 751-753
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Disclaimer
Please ask your physician for a reliable diagnosis. This website is only meant as a reference.
Prof. Dr. med. Peter Altmeyer