Angioedema Activity Score

The Angioedema Activity Score (AAS) is recommended by the EAACI/GA2LEN/EDF/WAO guidelines for urticaria as a standard measure for assessing disease activity in patients with recurrent angioedema. To date, it has been translated into 80 languages and used in 52 countries. It refers to a patient record by which activity and duration of angioedema is recorded and thus apparent to the physician providing care.

Have you had any swelling in the last 24 hours?

• yes
• no

During what period(s) did the swelling(s) exist? (please select all periods that apply)

• 0 - 8 o'clock
• 8 - 16 o'clock
• 16 - 24 o'clock

How severe are or were the physical discomforts (e.g., pain, burning, itching) caused by the swelling(s)?

• none
• mild
• medium
• severe

Can or have you been able to perform your daily activities due to the current swelling(s)?

• no restriction
• slight restriction
• medium restriction
• Activities not possible

Do you feel or did you feel cosmetically affected by the current swelling(s)?

• no
• slight
• medium
• severe

Overall, how severe would you rate the current swelling?

• negligible
• light
• medium

1. Kulthanan K et al (2019) Angioedema Activity Score (AAS): A Valid and Reliable Tool to Use in Asian Patients. Biomed Res Int 9157895.
2. Morioke S et al (2021) A validation study of the Japanese version of the Angioedema Activity Score (AAS) and the Angioedema Quality of Life Questionnaire (AE-QoL). Allergol Int 70:471-479.