Amodiaquines

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Definition
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Antimalarials.

Half-life
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5 h

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Indication
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Malaria therapy, especially for chloroquine resistance.

Notice! Increased cross-resistance to chloroquine has been described.

Dosage and method of use
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  • Initially 600 mg/day, then 300 mg after 6, 24 and 48 hours p.o.
  • Children initial 10 mg base/kg bw, then 5 mg base/kg bw after 6, 24 and 48 hours p.o.

Undesirable effects
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Vomiting, diarrhea, loss of balance. Rarely agranulocytosis, pancytopenia, corneal and nail pigmentation, retinopathy, polyneuropathy, liver damage.

Contraindication
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Pregnancy, lactation, known liver damage, blood disorders.

Preparations
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Flavoquin (only available through the international pharmacy)

Outgoing links (1)

Chloroquine;

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Last updated on: 29.10.2020