Alopecia areata universalis L63.1

Most severe, generalized form of alopecia areata with reversible, sometimes even irreversible loss of all body hair over time.

Glucocorticoids, systemic ones such as prednisolone (e.g. Decortin H) in low to medium dosage over a limited period of time. Zinc hydrogen aspartate (e.g. Unizink) 2 times/day 50 mg p.o. S.a. Alopecia areata.

Alternatively: Methylprednisolone i.v. (high dosage - 500mg/day i.v.) in a monthly interval therapy over 3 months.

1. Kaelin U et al (2006) Treatment of alopecia areata partim universalis with efalizumab. J Am Acad Dermatol 55: 529-532
2. Smith A et al (2015) High Relapse Rates Despite Early Intervention with Intravenous Methylprednisolone Pulse Therapy for Severe Childhood Alopecia Areata. Pediatr Dermatol doi: 10.1111/pde.12578.
3. Lux-Battistelli C (2015). Combination therapy with zinc gluconate and PUVA for alopecia areata totalis: an adjunctive but crucial role of zinc supplementation. Dermatol Ther doi: 10.1111/dth.12215