Synonym(s)
Agouti-Signaling Protein; Agouti signalling protein
DefinitionThis section has been translated automatically.
Signal protein, abbreviated ASP or ASIP, which plays an important role in the control of eumelanin. The typical banded coat pattern of domestic cats is called "agouti" (also wild-coloured). The agouti-signalling protein is encoded by the agouti gene and influences the distribution of black and yellow pigments in skin and hair. By mutations of the gene locus the yellow band of the single hair either spreads (agouti) or is completely lost (non-agouti).
Note(s)This section has been translated automatically.
Agouti is named after the Agutis, South American rodents that show light and dark banding of individual hairs.
Prof. Dr. med. Peter Altmeyer