Synonym(s)
acquired agammaglobulinemia; Immune deficiency syndrome Acquired immune deficiency syndrome; Immunodeficiency
DefinitionThis section has been translated automatically.
Family history of antibody deficiency syndrome in young girls and older women with a reduction in IgA, IgG and IgM.
Clinical featuresThis section has been translated automatically.
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DiagnosisThis section has been translated automatically.
IgA, IgG and IgM in the serum is reduced.
TherapyThis section has been translated automatically.
Gamma-globulin substitution (e.g. Intratect) 0.1-0.8 g/kg bw/day every 3-4 weeks, initially start with double the dose (IgG level in plasma should be at least 2 g/l), if necessary prophylactically antibiotics.
Note(s)This section has been translated automatically.
The clinical picture described here is probably identical with the variable immunodeficiency syndrome.
LiteratureThis section has been translated automatically.
- Al-Herz W et al (2003) Antibody response in common variable immunodeficiency. Ann Allergy Asthma Immunol 90: 244-247
- Barton JC et al (2003) Common variable immunodeficiency and IgG subclass deficiency in central Alabama hemochromatosis probands homozygous for HFE C282Y. Blood Cells Mol Dis 31: 102-111
- Sewell WA et al (2003) Therapeutic strategies in common variable immunodeficiency. Drugs 63: 1359-1371
- Sidwell RU et al (2002) A case of common variable immunodeficiency presenting with furunculosis. Br J Dermatol 147: 364-367
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