Synonym(s)
Adefovirdipivoxil; Adefovir Dipivoxil
DefinitionThis section has been translated automatically.
Virustatic agent from the class of nucleotidal reverse transcriptase inhibitors.
IndicationThis section has been translated automatically.
Chronic hepatitis B in adults with decompensated liver disease or compensated liver disease with proven active viral replication, continuously elevated ALT levels and histological evidence of active hepatitis and fibrosis.
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Pregnancy/nursing periodThis section has been translated automatically.
If possible, do not use in pregnancy (reproductive toxic effects in animal experiments, insufficient data available in patients), contraindicated in lactation.
Dosage and method of useThis section has been translated automatically.
once/day 1 tbl. p.o.
Remember! Stop of therapy can be considered in case of seroconversion (loss of HBeAg and HBV-DNA in case of anti-HBe detection in 2 consecutive controls!
ContraindicationThis section has been translated automatically.
Hypersensitivity to Adefovir, Pat. < 18 years (insufficient data available, Pat. > 65 years (no studies).
PreparationsThis section has been translated automatically.
Hepsera
Note(s)This section has been translated automatically.
Remember! During therapy control of biochemical, virological and serological hepatitis B markers at least every 3-6 months!
Prof. Dr. med. Peter Altmeyer