Pustulosis, acute generalized exanthematous: foudroyantes exanthema occurring 3 days after a highly febrile streptococcal infection (angina tonsillaris) with extensive erythema and red plaques as well as numerous, dense, 0.1-0.3 cm large, bizarre, flat, white pustules which are not attached to the follicles and burst rapidly (leaving extensive erosions); reduced AZ; leukocytosis (> 15,000/µl); neutrophilia.
Pustulose, acute generalized exanthematic. acute erythrodermia with histologically proven pustular formation in a 75-year-old female patient after drug administration (vemurafenib). pustular formation histologically proven. now subclinical. detectable by exfoliative (coarse lamellar) scaling on the left upper arm. keratosis areolae mamillae.
Pustulosis, acute generalized exanthematic (AGEP). pustules only visible in places. already advanced healing process. typical for this is the coarse lamellar (parchment-like) desquamation of the skin.
Pustulosis, acute generalized exanthematous: large-area exanthema with histologically proven subcorneal pustular pustular formation, now coarse lamellar desquamation.
Pustulosis, acute generalized exanthematic: large-area exanthema which occurs acutely after drug administration and has histologically proven subcorneal pustular formation.
Pustulosis, acute generalized exanthematous: acutely occurring erythrodermal exanthema with histologically proven subcorneal pustular formation in a 62-year-old patient. exfoliative (coarse lamellar) scaling.
Pustulosis, acute generalized exanthema: largegeneralized exanthema with histologically proven pustular formation in a 74-year-old female patient.
Pustulosis, acute generalized exanthematic. bizarrely configured (subcorneal), easily vulnerable and rapidly bursting sterile pustules on erythematous ground.
Pustulosis, acute generalized exanthematic. extensive detachment of the skin, numerous pustules at the edges on flat erythema. explanation see following figure
Pustulose acute generalized exanthematic: explanations see fig.
Pustulosis, acute generalized exanthematous. large-area exanthema, acutely occurring after medication, with histologically proven subcorneal pustular formation; formation of pus puddles; coarse lamellar scaling.
Pustulosis, acute generalized exanthematous: acutely occurring erythrodermal exanthema with histologically proven subcorneal pustular formation in a 62-year-old patient. Exfoliative (coarse lamellar) scaling. areas of weeping in places.
Pustulosis, acute generalized exanthematous: large-area exanthema with histologically proven subcorneal pustular pustular formation, which occurs acutely after medication intake, extensive blistering of the palms with coarse lamellar scaling.
Pustulosis, acute generalized exanthematous: acutely occurring erythrodermal exanthema with histologically proven subcorneal pustular formation in a 62-year-old patient. Exfoliative (coarse lamellar) scaling. massive swelling of the lower legs.
pustulosis acute generalized exanthematic: detailed view of the foot. besides small deep red papules and plaques, pustules and extensive pus puddles. affected area painful. walking not possible.
Pustulosis, acute generalized exanthematous. healing of the skin lesions on the neck with a coarse, exfoliative (parchment-like) desquamation in a 74-year-old female patient. this type of desquamation can also be observed in other skin diseases associated with subcorneal pustular pustules.
pustulose, acute generalized exanthematic skin in healing. characteristic detachment of coarse lamellar skin fragments from finest thin translucent horny foils. this type of scaling indicates a detachment of very superficial horny layers (corneolytic).
Pustulose acute generalized exanthematic: Marking of the site of withdrawal: Arrow marks the centrally located pustule, blue line marks the "pimple-free" zone which is necessary for technical reasons.
Pustulosis acute generalized exanthematic: subcorneal pustule with neutrophil granulocytes; for a meaningful biopsy it is of great importance to keep the corneum intact (Remark: removal of a small central pustule with a non-pustular rim)
pustulose acute generalized exanthematic: encircles the subcorneal pustule with neutrophil granulocytes. the "roof" of the pustule is formed by the lifted stratum corneum. arrow marks the zone of later desquamation. the underlying epithelium (marked by bars) remains intact and is not detached. this explains the very thin, foil-like scaling
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