Acanthosis nigricans, drug-induced L83.x

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 21.12.2021

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Definition
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Rare variant of acanthosis nigricans induced by certain drugs.

Etiopathogenesis
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Triggered by drugs, e.g. systemic glucocorticoids, nicotinic acid, estrogens, insulin, methyltestosterone, oral contraceptives, fusidic acid, folic acid antagonists. Interactions between these drugs with lipid metabolism are postulated. Furthermore, an overstimulation of receptor tyrosine kinases by the above mentioned drugs might play a role.

Therapy
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Stopping the triggering medication. Symptomatic therapy if necessary. S.a.u. Acanthosis nigricans.

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Last updated on: 21.12.2021