Tris-biphenyl triazines (nano)

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

1,3,5-Triazine, 2,4,6-Tris([1,1'-Biphenyl]-4-yl); 2,4,6-Tris([1,1'-biphenyl]-4-yl)-1,3,5-triazin; CAS number: 31274-51-8-; TBPT

Definition
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TRIS-BIPHENYL TRIAZINE (NANO), short TBPT, is a colourless organic solid which is almost insoluble in water and only slightly soluble in cosmetic oils. TBPT is used as a nano product (particle size < 100nm) mainly in sun protection products as well as in various skin care products with UV protection, e.g. day creams. The maximum concentration of TBPT is 10 %. The absorption spectrum covers the complete UVB range (280-320nm) and in the UVA range the spectrum between 320-340nm (UVA2 range) with an absorption maximum at 310nm.

Preparations
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Tinosorb A2B®

Note(s)
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Organic light protection filters are all those UV filters whose effect is not exclusively based on the inorganic, physically active substances titanium dioxide or zinc oxide. Organic, also known as chemical UV filters, are photoactive substances that are able to absorb light quanta in a certain wavelength range (ultraviolet radiation in the range of about 280 to 400 nm = ultraviolet radiation = UVB/UVA spectrum). The absorbed UV is then released as thermal energy without penetrating the skin. In this reversible photoisomerization, the energy of the absorbed photon must correspond to the energy required to lift an electron in the molecule of the filter substance from a lower to a higher orbit. In order to protect over the entire width of the wavelengths relevant to humans from 290 to 400 nm, several chemical filters with different absorption maxima are usually combined. With a suitable combination of organic and physical filters, the content of organic filters can also be reduced with the same UV protection. This is desirable, since especially photounstable organic UV filters can cause phototoxic and photoallergic reactions depending on their concentration in the finished product.

Literature
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  1. Couteau C et al (2015) Tris-biphenyl triazine, a new ultraviolet filter studied in terms of photoprotective efficacy. Int J Pharm. 487:120-123.

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Last updated on: 29.10.2020