Proline (inci)

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

2-pyrrolidone carboxylic acid; CAS number: 147-85-3; Proline; Prolinum

Definition
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A proteinogenic amino acid which is non-essential for mammals and has the molecular formula C5H9NO2, which has a special function for the tertiary structure of proteins. Proline is an essential component of collagen and gliadin.

Important derivatives are hydroxyproline (important component of collagen) or 4-methylproline a building block for antibiotics.

Proline is used in cosmetic formulations. The amino acid acts as an antistatic agent (reduces static electricity by neutralizing the electrical charge on the surface of the hair) and as a combability aid (reduces or prevents tangling of the hair due to changes or damage on the hair surface and thus improves combability).

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Gliadin;

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Last updated on: 29.10.2020