Poloxamer 407 (inci)

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

CAS number: 9003-11-6

Definition
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Poloxamers" are low-foaming and foam-absorbing, non-ionic surfactant block polymers composed of polyethylene oxides and polypropylene oxides. Poloxamers are used for dispersion and emulsification in cosmetics (also in the chemical-technical industry and medicine). The polyethylene oxide part of the polymer is water-soluble, whereas the polypropylene oxide part is not, so that this results in the special amphiphilic properties of the compounds.

Poloxamer 407 is a white, waxy powder which is used in cosmetic formulations. The substance acts as an emulsifier (surface-active substance which is used in cosmetic products as an auxiliary agent to combine two immiscible liquids - e.g. oil and water - into one emulsion) and as a surfactant (washing-active substance; improves the even distribution of the products during application).

Literature
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  1. Ammon HPT et al (2014) Hunnius Pharmaceutical Dictionary 11th Edition Walter de Gruyter Berlin-New York p. 1431
  2. v. Bruchhagen F et al (1994) Hager's Handbook of Pharmaceutical Practice. Springer Verlag, Berlin, Heidelberg, New York S 284-285

Outgoing links (2)

Emulsifiers; Surfactants;

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Last updated on: 29.10.2020