Synonym(s)
1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1H)-pyridone monoethanolamine salt; CAS number: 68890-66-4; Piroctone Olamine; Piroctones Ethanolamine; Piroctonolamine
DefinitionThis section has been translated automatically.
Piroctone olamine is the synthetic ethanolamine salt of the pyridone derivative "Piroctone". Piroctone olamine is used as a preservative in cosmetic formulations. The substance inhibits the growth of microorganisms. Piroctone olamine dissolves in surfactants. This enables the active agent to be used in shampoos ( Preparations: Octopirox®). The substance is used in numerous dandruff shampoos.
Note(s)This section has been translated automatically.
The framework conditions for preservatives that may be used in cosmetics are defined in the EC Cosmetics Regulation - 1223/2009 - Annex V.
Medically Piroctone olamine is used because of its fungicidal and antibacterial effects.
LiteratureThis section has been translated automatically.
- The Federal Office of Consumer Protection and Food Safety (BVL) Manage risks - protect consumers: https://www.bvl.bund.de/DE/03_Verbraucherprodukte/03_AntragstellerUnternehmen/02_Kosmetik/04_Inhaltsstoffe/bgs_fuerAntragsteller_kosmetik_gesetzlicheRegelung_inhaltsstoffe_node.html
- Pierard-Franchimont C et al (2002) Nudging hair shedding by antidandruff shampoos. A comparison of 1% ketoconazole, 1% Piroctone olamine and 1% zinc pyrithione formulations. International Journal of Cosmetic Science24: 249-256.
Prof. Dr. med. Peter Altmeyer