Lithium gluconate (inci)

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

CAS number: 60816-70-8; Lithium D-gluconates

Definition
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Gluconate refers to salts of gluconic acid. Lithium is a chemical element (light metal) from the group of alkali metals.
Lithium gluconate is used in cosmetic formulations. It has a skin caring effect. Furthermore, it is used in an 8% application form for def seborrhoeic dermatitis (Dreno B et al. 2003).

Effects
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In an "intent-to-treat analysis (ITT)" a clinical superiority of an 8% lithium gluconate cream compared to a 2% ketoconazole cream could be proven in a larger collective (n=269 patients) in seborrheic dermatitis (Dreno B et al. 2003).

Sesderma -Sebovalis Facial Cream is available as a ready-to-use preparation (international pharmacy).

Recipe(s)
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Rp. Lithium gel.

  • Lithium gluconate 8.0 g
  • Glycerol 10.0 g Carbomer 1.5 g
  • Sodium hydroxide qs pH 6.8
  • Methyl paraben 0.10 g Propyl paraben 0.05 g
  • Propylene glycol 5.0 g
  • Aqua purificata qs 100.0 g

Literature
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  1. Dreno B et al (2003) Lithium gluconate 8% vs ketoconazole 2% in the treatment of seborrhoeic dermatitis: a multicentre, randomized study. Br J Dermatol 148:1230.

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Last updated on: 29.10.2020