Lactoperoxidase (inci)

The enzyme lactoperoxidase (LPO), a peroxidase, is found in most animals and is produced in humans by the mammary glands, salivary glands and mucous glands of the bronchi. Lactoperoxidase catalyses the oxidation of phenols and various anions by hydrogen peroxide. The reaction products are highly reactive and have a toxic effect on microorganisms that have entered the body.

LPO is therefore an important component of the innate (non-specific) immune system and enables the neutralisation of bacteria in milk and other mucous membrane secretions. The "lactoperoxidase system appears" to act synergistically with lactoferrin or lysozyme.

Due to the broad (non-specific) antibacterial activity of the lactoperoxidase system, the enzyme is used for the preservation of food and cosmetics. Furthermore, lactoperoxidase is used for the treatment of caries, gingivitis and periodontitis. It is therefore found as a component of toothpastes and mouth rinses.