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Isoamyl-4-methoxycinnamates (inci)

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Amiloxate; CAS number: 71617-10-2; Isoamyl p-methoxycinnamates (INCI-Kennzeichnung); Isopentyl p-methoxycinnamates; p-Methoxycinnamic acid oamyl ester

Definition
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Isoamyl p-methoxycinnamate, the ester of isoamyl alcohol with methoxy-cinnamic acid, is a substance used in cosmetic formulations. The substance acts as a UV absorber and protects the cosmetic product from UV light. In connection with sunlight allergic reactions may occur (see below photo contact allergy).

Note(s)
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The framework conditions for UV filters that may be used in cosmetics are defined in the EC Cosmetics Regulation (1223/2009) Annex VI.

Literature
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  1. Ghazavi MK et al (2011) Photo-allergic contact dermatitis caused by isoamyl p-methoxycinnamate in an 'organic' sunscreen. Contact Dermatitis 64:115-116
  2. Hagedorn-Leweke U et al (1995) Absorption of sunscreens and other compounds through human skin in vivo: derivation of a method to predict maximum fluxes. Pharm Res 12:1354-1360.
  3. Monzón S et al (2009) Photoallergic contact dermatitis due to isoamyl-p-methoxycinnamate. J Investig Allergol Clin Immunol 19:415-416

Outgoing links (1)

Photoallergic dermatitis;

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Last updated on: 29.10.2020