Butyl methoxydibenzoylmethanes

Author:Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

1-[4-(1,1-Dimethylethyl)phenyl]-3-(4-methoxyphenyl)propane-1,3-diones; 4-tert-butyl-4-methoxy-dibenzoylmethane; Avobenzone; BMDBM; butylmethoxydibenzoylmethane; CAS number: 70356-09-1

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DefinitionThis section has been translated automatically.

Butyl methoxydibenzoylmethane, or BMDBM and avobenzone for short, is a substituted 1,3-diketone. Butyl methoxydibenzoylmethane is a soluble organic UV filter which absorbs UV-A rays of about 320 to 400 nm with an absorption maximum at 357 nm (UVA range). The maximum concentration of butyl methoxydibenzoylmethane in cosmetic applications is 5%.

Due to the photoreactivity the light protection effect of butyl methoxydibenzoylmethane decreases. This reduction in function can be reduced by adding photostable organic UV filters as e.g. bis-ethylhexyloxyphenol methoxyphenyl triazine (Tinosorb S) (Chatelain E et al. 2001). Contact sensitizations by butyl methoxydibenzoylmethanes have been described (de Groot AC et al. 1987).

PreparationsThis section has been translated automatically.

Butyl methoxydibenzoylmethane, under the name "avobenzone", is the most important UV-A filter in sunscreens on the American market.

LiteratureThis section has been translated automatically.

  1. Chatelain E et al (2001) Photostabilization of butyl methoxydibenzoylmethane (Avobenzone) and ethylhexyl methoxycinnamate by bis-ethylhexyloxyphenol methoxyphenyl triazine (Tinosorb S), a new UV broadband filter. Photochemical photobiol 74:401-406.
  2. Gange RW et al (1986) Efficacy of a sunscreen containing butyl methoxydibenzoylmethane against ultraviolet A radiation in photosensitized subjects. J Am Acad Dermatol15:494-499.
  3. de Groot AC et al (1987) Contact allergy to butyl methoxydibenzoylmethanes. Contact dermatitis 16:278.

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Last updated on: 29.10.2020