DefinitionThis section has been translated automatically.
Tranexamic acid is a synthetic antifibrinolytic agent that specifically inhibits fibrinolysis without interfering with other proteolytic processes.
Pharmacodynamics (Effect)This section has been translated automatically.
The principle of action consists in blocking the specific lysine binding site on the plasminogen. This prevents the binding to fibrin and interrupts fibrinolysis. Derivatives that differ in their specific activity are paraaminomethylbenzoic acids, tranexanoic acid and epsilon-aminocaproic acid.
PreparationsThis section has been translated automatically.
Cyclocapron®
LiteratureThis section has been translated automatically.
- HA Neumann (2014) The coagulation system. ABW-Scientific Publisher GmbH Berlin
Prof. Dr. med. Peter Altmeyer