Thromboxane b2

Prostaglandins, PGs, are almost ubiquitously present in the organism and are characterized by a broad pharmacological spectrum of activity. Prostaglandins belong to the eicosanoids and act as so-called tissue hormones. They are normally not stored in the various organs and cells, but are newly synthesized and released in response to various stimuli.

Thromboxane A2, also called TXA2, which is formed by the thromboxane synthase from prostaglandin-H2, mediates its effects via the thromboxane receptor, a membrane-bound G-protein coupled receptor. The half-life of active thromboxane A2 in the body is short and is 30 seconds. Thromboxane A2 is then degraded to the inactive thromboxane B2.