Shwartzman reactionD69.8

Author:Prof. Dr. med. Peter Altmeyer

Last updated on: 29.10.2020

Synonym(s)

Ebbi Swartzman phenomenon; Sanarelli-Shwartzman reaction; Shwartzman Phenomenon; Shwartzman reaction; Shwartzman-Sanarelli reaction

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HistoryThis section has been translated automatically.

Sanarelli, 1924 (first description of the generalized form); Shwartzman, 1928 (first description of the localized form)

DefinitionThis section has been translated automatically.

Shock and adrenal cortex necrosis after 2 injections of Gram-negative bacteria within 24 hours.

EtiopathogenesisThis section has been translated automatically.

Lipopolysaccharides ( LPS of the bacterial membrane) lead to the activation of monocytes and release of tumor necrosis factors and interleukin-1.

LiteratureThis section has been translated automatically.

Ramirez-Hernandez C et al (2004) Mast cell density during initiation and progression of the local Shwartzman reaction. Inflamm Res 53: 107-110
Riemekasten G et al (2002) Shwartzman phenomenon in a patient with active systemic lupus erythematosus preceding fatal disseminated intravascular coagulation. Lupus 11: 204-207
Shwartzman G (1928) A new phenomenon of local skin reactivity to B. typhosus culture filtrate. Proc Soc Exp Biol Med 25: 560-561

Authors

Last updated on: 29.10.2020

Author: Prof. Dr. med. Peter Altmeyer