Sensitization, clinically mute

The term sensitization requires a positive epicutaneous test (ECT), i.e. a papulo-vesicular reaction with crescendo character, in the case of a contact allergy (type IV reaction). In the case of clinically silent sensitization, relevant clinical symptoms are absent despite clinical exposure to the contact allergen, in the case of doubtlessly proving ECT. If a clinically silent sensitization is proven and an occupational cause can be assumed, then this also becomes relevant for MdE, since an individually increased risk can be assumed.