Rhinitis local allergic J30.1

Local allergic rhinitis, also known as the phenomenon of "exclusively local IgE production", is characterized by chronic "idiopathic" rhinitis in which the serological allergy tests, as well as prick and intradermal tests, are negative. Positive reactions to nasal provocation can be detected as an indication of local IgE production.

Patients respond less well to systemic therapy with oral antihistamines.

1. Forester JP et al (2010) Local production of IgE in the respiratory mucosa and the concept of entopy: does allergy exist in nonallergic rhinitis? Ann Allergy Asthma Immunol 105:249-255
2. Gelardi M et al (2916) Local allergic rhinitis: entopy or spontaneous response? World Allergy Organ J 9:39.