Pneumonia, eosinophilic chronicJ18.9
Synonym(s)
DefinitionThis section has been translated automatically.
Chronic eosinophilic pneumonia is a rare, aetiologically unexplained disease associated with blood eosinophilia (in 80% of cases) as well as systemic symptoms such as fever, chills, night sweats, cough, loss of appetite and weight loss.
Occurrence/EpidemiologyThis section has been translated automatically.
w:m=2:1
EtiopathogenesisThis section has been translated automatically.
Often associated with allergic diathesis. Almost 50% of patients are preceded by bronchial asthma < 5 years.
Clinical featuresThis section has been translated automatically.
Chronic eosinophilic pneumonia (CEP) usually begins insidiously with systemic symptoms such as fever, chills, night sweats, cough, loss of appetite and weight loss. About 30% of patients suffer from bronchial asthma at the same time.
ImagingThis section has been translated automatically.
Thoracic radiographs often show peripheral (migrating) infiltrates.
LaboratoryThis section has been translated automatically.
Blood eosinophilia (80%), significant IgE increase, p-ANCA positivity (50%).
DiagnosisThis section has been translated automatically.
Clinical picture, chest x-ray, BAL with >40% eosinophilia .
TherapyThis section has been translated automatically.
High-dose systemic glucocorticoids
Progression/forecastThis section has been translated automatically.
Very short-term and significant improvement of symptoms (within 48h) after the start of glucocorticoid therapy.
LiteratureThis section has been translated automatically.
- Sriratanaviriyakul N et al (2016) Chronic eosinophilic pneumonia presenting with ipsilateral pleural effusion: a case report. J Med Case Rep 10:227.
- Hirai J et al (2017) Eosinophilic pneumonia caused by daptomycin: Six cases from two institutions anda
review of the literature. J Infect Chemother 23:245-249. - Kim NH et al (2015) Bronchial involvement in chronic eosinophilic pneumonia: a case report. J Thorac Dis 7: E97-E101
- Jaimes-Hernández J et al (2012) Chronic eosinophilic pneumonia: autoimmune phenomenon or immunoallergic disease? Case report and literature review. Reumatol Clin 8:145148.
Shin YS et al. (2012)Successful treatment of chronic eosinophilic pneumonia with anti-IgE therapy. J Korean Med Sci 27:1261-1264.