Synonym(s)
Multiple Myeloma Oncogene 1
DefinitionThis section has been translated automatically.
Oncogene which is located next to the IgH gene in the human myeloma cell line SKMM-1 as a result of a t-translocation (6;14) (p25; q32) An overexpression of the MUM1 mRNA was observed in this cell line. MUM-1 expression was detected in large B-cell lymphomas of the leg in about 60% of cases and thus plays a diagnostic role.
LiteratureThis section has been translated automatically.
- Grange F et al (2007) Primary cutaneous diffuse large B-cell-lymphoma, leg type. Arch Dermatol 143: 1144-1150
Prof. Dr. med. Peter Altmeyer