DefinitionThis section has been translated automatically.
Bronchoprovocation with methacholine to determine the one-second capacity (FEV1) (see provocation test)
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- Inhalation of smallest amounts of methacholine in ascending doses.
- After each inhalation, complete lung function measurement (recording of lung volume by spirometry).
- A drop in forced one-second capacity (FEV1) of at least 20% allows estimation of the severity of bronchial hyperreactivity.
- If bronchial constriction has occurred, application of a bronchodilator spray for inhalation. This makes it possible to classify the severity of the bronchial hypersensitivity.
LiteratureThis section has been translated automatically.
- Marogna M et al (2007) Long-lasting effects of sublingual immunotherapy for house dust mites in allergic rhinitis with bronchial hyperreactivity: A long-term (13-year) retrospective study in real life. Int Arch Allergy Immunol 142: 70-78
Prof. Dr. med. Peter Altmeyer