MaBy means of the growth factors M-CSF and GM-CSF, non-activated M-CSF and GM-CSF macrophages are formed. activation with IFNγ and LPS leads to inflammatory M1 macrophages with cytotoxic properties. activation with IL-4 and IL-10 leads to M2 macrophages. GM1 macrophages are formed by activation from GM-CSF macrophages.
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