Jones mote response

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Jones-Mote-reaction

Definition
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Little-used term for a cutaneous IgE-dependent inflammatory late reaction with pronounced involvement of basophilic granulocytes, whereby the reaction reaches its peak 24 h after renewed allergen contact.

Clinically, the reaction appears as a discrete erythematous area that persists for about 24 hours and then disappears without any residuals. Necrosis never occurs.

Literature
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  1. Askenase PW et al (1976) Basophils in tuberculin and "Jones-Mote" delayed reactions of humans. J Clin Invest 58:1145-1154.
  2. Biedermann T (2018) Basic principles of allergy and intolerance reactions. In: Braun-Falco`s Dermatology, Venerology Allergology G. Plewig et al. (Hrsg) Springer Verlag S 449-450

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Last updated on: 29.10.2020