Floor change

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Definition
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Spread of clinical symptoms and immunological/histological mucosal changes from the upper (nasal mucosa) to the lower airways (bronchi, bronchioles).

General information
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Clinical relevance has the floor change in allergic rhinitis. In about 20-50% of all untreated patients with allergic rhinitis, a floor change occurs within 5-15 years. In order to prevent the development of bronchial asthma, all causal therapy options for the treatment of allergic rhinitis should be optimally exploited. The unilateral change of levels towards asthma is the most frequent form; more rarely, the transition from rhinitis to sinusitis is possible.

Literature
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  1. Fuchs Th et al (2000) The allergen-specific immunotherapy. ENT 48: 59-67

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Last updated on: 29.10.2020