Endotoxin shockR57.8

Author:Prof. Dr. med. Peter Altmeyer

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Last updated on: 24.06.2024

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DefinitionThis section has been translated automatically.

Shock symptoms, caused by an infection with endotoxin-containing bacteria. Endotoxins are lipopolysaccharides (LPS) in the outer cell membrane of various Gram-negative bacteria.

EtiopathogenesisThis section has been translated automatically.

Interaction with monocytic cells in particular leads to the activation and release of interleukin-1, interleukin-6 and tumor necrosis factor-α in particular. This leads to an increase in temperature, collagenase production, histamine release, macrophage activation and activation of endothelial cells.

Clinical featuresThis section has been translated automatically.

Fever, leukopenia, drop in blood pressure, intravascular coagulation.

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Last updated on: 24.06.2024