DefinitionThis section has been translated automatically.
Widespread NSAID (non-steroidal antiinflammatory drug) with pronounced analgesic, antipyretic, antiphlogistic opioid-sparing effect. Also possible as an analgesic booster to paracetamol or metamizole (balanced analgesia).
IndicationThis section has been translated automatically.
- Inflammation, painful swelling, rheumatoid arthritis, arthrosis.
- Since increased COX 2 levels in carcinoma in situ, type "actinic keratosis" can be detected (also in spinocellular carcinomas), a 3% local therapeutic agent (diclofenac-hyaluronic acid gel) is successfully used for actinic keratoses.
You might also be interested in
Dosage and method of useThis section has been translated automatically.
2 times/day 50-150 mg p.o., i.m., i.v.
Undesirable effectsThis section has been translated automatically.
- Systemic therapy: gastrointestinal ulcers, exanthema, photosensitivity.
- With local application: redness, itching and rarely allergic contact reactions.
PreparationsThis section has been translated automatically.
- Voltaren, Duravolten, Effekton, Diclofenac-ratiopharm
- Solaraze (local therapeutic agent)
Note(s)This section has been translated automatically.
The combination of diclofenac with another mixed NSAID like ibuprofen/naproxen (inhibition of cyclooxygenases 1 and 2) or a selective COX-2 inhibitor like parecoxib is contraindicated.
LiteratureThis section has been translated automatically.
- Jage J (2009) Key questions on the therapy of postoperative pain. Georg Thieme Publishing House, Stuttgart S.16-21
- Merk HF (2007) Topical diclofenac in the treatment of actinic keratoses. Int J Dermatol 46: 8-12
Prof. Dr. med. Peter Altmeyer