Coeruloplasmin

Author:Prof. Dr. med. Peter Altmeyer

All authors of this article

Last updated on: 29.10.2020

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DefinitionThis section has been translated automatically.

A copper oxidizing enzyme which is bound in the liver and migrates in the alpha2-globulin fraction in serum electrophoresis.

Its functions are:

  • Binding of copper (Cu) in plasma and Cu transport n tissue.
  • Influence on the redox status of plasma, antioxidant effect.
  • Acute phase protein in inflammation
  • Regulation of the ion ion status of iron

General informationThis section has been translated automatically.

Standard values: In serum the standard value is between 20 and 60 mg/dl or 0,94 and 3,75 µmol/l

Pathologically increased in: neoplasia, pregnancy, cholestasis, acute inflammation. In serum electrophoresis there is an increase in the alpha2-globulin fraction.

Note: The use of oral contraceptives leads to a dose-dependent 20-30% increase in serum Cp concentration.

Pathologically decreased: liver cirrhosis, nephrotic syndrome, Wilson's disease

Authors

Last updated on: 29.10.2020

Author: Prof. Dr. med. Peter Altmeyer