Chylomic crown

Chylomicrons (from Greek chylos=juice and mikros=small) are small lipoprotein particles of 0.5 to 1.0 µm in diameter. They are formed in the endoplasmic reticulum of the small intestine epithelia. Chylomicrons serve as a transport form for the enteral ingested food fats, which bypass the portal blood stream and enter the large bloodstream via the lymphatic system. Chylomicrons coat the lipids with a cholesterol-containing phospholipid envelope. In this phospholipid envelope, various apolipoproteins act as structural elements, such as the apolipoproteins AIV, B48, CII, CIII and E . The 240 kd sized apolipoprotein B48 forms an amphiphilic envelope with a hydrophilic outer layer. The lipid core of the chylomicron contains mainly triacylglycerides and a smaller amount of cholesterol esters.

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