Chronic inducible urticaria

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

chronic inducible urticaria; CindU

Definition
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Urticaria in which the triggering causes are known or easily determined. It is the opposite of chronic spontaneous urticaria.

Classification
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Chronic inducible urticaria (causes known or easily determined e.g. physical urticaria etc.):

  • Urticaria, physical (inducible):Mechanical:
    • Urticaria factitia (most frequent form of physical urticaria)
    • Pressure Urticaria
    • Vibratory Urticaria/Angioedema.
  • thermal:
    • Cold urticaria (contact type; second most common form of physical urticaria)
    • Thermal urticaria (heat contact urticaria)
  • Electromagnetic waves:
    • Light urticaria (solar urticaria)
    • Radiolucent urticaria
  • Other forms of urticaria:
    • Urticaria, cholinergic
    • Urticaria, exertion urticaria
    • Contact urticaria
      • Contact urticaria, non-allergic (e.g. caused by nettles, mites)
      • Contact urticaria, allergic (e.g. due to latex, animal hair)
      • Urticaria, aquagene.

Therapy
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See under the respective clinical pictures.

Omalizumab: A literature review of 43 studies, case studies, case reports and analyses on the use of amalizumab in various diseases was conducted. Subtypes of chronically inducible urticaria (symptomatic dermographism, cold, heat, sun, water and pressure urticaria, vibratory angioedema, cholinergic urticaria and contact urticaria). This resulted in clear therapy effects with the strongest evidence in symptomatic dermographism, cold urticaria, sun urticaria (Maurer M et al. 2018)

Literature
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  1. Maurer M et al (2018) Omalizumab treatment in patients with chronic inducible urticaria: A systematic review of published evidence. J Allergy Clin Immunol 141:638-649.

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Last updated on: 29.10.2020