Chelidonin

Alkaloid that can be obtained from the latex of Chelidonium majus, the celandine.

Chelidonium majus contains numerous alkaloids including berberin, chelerythrin, chellidonin, coptisin, spartein, chellidoxanthin and sanguinarin. The alkaloids are present both in the above-ground parts of the plant and in the root.

Celandine extracts have in vitro toxic effects on viruses, bacteria, fungi and weakly cytotoxic effects on human cells (the cause is the content of chellidonin, coptisin and protopin).

Cheldonin has a morphine-like, but much weaker central calming, spasmolytic and analgesic effect.

In folk medicine, the lactic juice of the plant is used externally for skin diseases such as warts, either natively or as an ointment.

The native juice is applied to a wart once a day for several days. The effectiveness of the therapy has been proven several times.