Butylcatechin, 4-tertiary

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

4-tertiary butylbenzcatechol; para-tertiary-butylcatechol; PTBC; p-tertiary butylcatechol

General information
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  • Chemical compound with potent contact allergenic effect from the group of catechols. Use among other things as an additive in paints, as an antioxidant in mineral oil products, lubricating oils, in the production of plastics (polymerisation inhibitor) from polyester resins and polyvinyl chloride (PVC), in the paper industry (component of the pressure-sensitive microcapsule coating; agent for retarding the light-induced decolourisation of the dye formed), in the rubber industry (stabiliser for synthetic rubber).
  • The test concentration in the epicutaneous test is 0.25% (Vaseline as the basis).

Note(s)
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Cases of contact allergies have been observed in the rubber, paint, mineral oil and plastics industries. According to individual case descriptions and older studies, occasional triggering of Vitiligo and Leukoderm.

Literature
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  1. Hillen U et al (2003) Optimizing the patch-test concentration of para-tetriary-butylcatechol: results of a prospective study with dilution series. Contact dermatitis 48: 140-143

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Last updated on: 29.10.2020