Butyl-methoxydibenzoylmethanes

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

4-tert-butyl-4'-methoxy-dibenzoylmethane; Avobenzonum; BMDM; butylmethoxydibenzoylmethane; Butyl Methoxydibenzoylmethanes (INCI-Kennzeichnung)

Definition
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Butyl Methoxydibenzoylmethane, also called Avobenzone (trade names: Parsol 1789, Milestab 1789, Eusolex 9020, Escalol 517) belongs to the group of chemical light protection filters that absorb the entire UVA spectrum. The absorption maximum is 357 nm. Butyl-methoxydibenzoylmethane is a dibenzoylmethane derivative with high photosensitizing potency. Hormonal effects are also attributed to the substance.

Literature
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  1. European Multicentre Photopatch Test Study (EMCPPTS) Task Force. A European multicentre photopatch test study. Br J Dermatol 166:1002-1009
  2. Trotta V et al (2014) Influence of lipid microparticle encapsulation on in vitro efficacy, photostability and water resistance of the sunscreen agents, octyl methoxycinnamate and butyl methoxydibenzoylmethane. Drug Dev Ind Pharm 40:1233-1239
  3. Montenegro L et al (2013) Evaluation of sunscreen safety by in vitro skinpermeation studies: effects of vehicle composition. Pharmacy 68:34-40

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Last updated on: 29.10.2020