Benzisothiazolinone

Author:Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

1,2-benzisothiazolin-3-one; Sodium salt

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DefinitionThis section has been translated automatically.

Widely used biocide and technical preservative with microbicidal and fungicidal action.

General informationThis section has been translated automatically.

  • Used as a preservative in emulsion paints, varnishes, adhesives, detergents, fuels and in paper production. The dosage is 200-400 ppm depending on the area of application and combination with other biocides.
  • Gloves made of polyvinyl chloride (PVC) often contain benzisothiazolinone (mostly in low concentrations < 50-250 ppm) and may cause contact allergies. Here, occlusion probably plays a decisive role in triggering the contact allergy.
  • In case of clinical suspicion an epicutaneous test should be performed.

LiteratureThis section has been translated automatically.

  1. Aalto-Korte K et al (2006) Antimicrobial allergy from polyvinyl chloride gloves. Arch Dermatol 142: 1326-133

  2. Kaur-Knudsen D et al (2012) Systemic allergic dermatitis following airborne exposure to 1,2-benzisothiazolin-3-one. Contact dermatitis 67:310-312

Authors

Last updated on: 29.10.2020

Author: Prof. Dr. med. Peter Altmeyer