Aminotransferases

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

ALT/GPT; AST/GOT

Definition
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Aminotransferases, also called transaminases, are enzymes of the EC classification. They catalyze the exchange of amino groups between amino acids and α keto acids. The two most important enzymes are alanine aminotransferase (ALT, GOT) and asparagine aminotransferase (AST, GPT)

General information
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Standard value: The standard value of alanine aminotransferase is up to 50 U/l for men and 35 U/l for women.
The standard value of asparagine aminotransferase

Pathologically increased: Liver abscess, liver cirrhosis, liver carcinoma and metastases, non-alcoholic fatty liver, fatty liver hepatitis, drug icterus, alcoholic and other toxic hepatopathies, autoimmune hepatitis, intra- and extrahepatic cholestasis, primary biliary cirrhosis, primarily sclerosing cholangitis, acute, chronically aggressive and persistent viral hepatitis, concomitant hepatitis, liver congestion, malignant hyperthermia, hypothyroidism, pulmonary artery embolism, heart muscle diseases, skeletal muscle diseases

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Last updated on: 29.10.2020