DefinitionThis section has been translated automatically.
The alpha-2-macroglobulin is a coagulation inhibitor, which is present in the plasma in a concentration of 150-300mg/dl. Its molecular weight is 725,000 D. It is synthesized in the liver and has a half-life of about two to three days. Furthermore, the alpha-2-macroglobulin converts the complex of antithrombin III with the activated serine proteases into a stable compound and inhibits factor Xa. It does not competitively inactivate plasmin. It is located in the plasma and on the platelet membrane.
General informationThis section has been translated automatically.
Standard value: The standard value is between 1.3 and 3.0 g/l in serum
LiteratureThis section has been translated automatically.
- HA Neumann (2014) The coagulation system. ABW-Wissenschaftsverlag GmbH Berlin p. 113.
Prof. Dr. med. Peter Altmeyer